Science
Orexin: The Brain's Master "Stay Awake" Switch
Discover how orexin controls wakefulness, why losing it causes narcolepsy, and how new sleep drugs target this powerful brain system.
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Roon Team
July 4, 2026·11 min read
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Research-backed breakdowns of clinical studies, neurotransmitters, and how your brain actually works.
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AMPA Receptors and Memory: The Science Behind "Ampakine" Nootropics
Discover how AMPA receptor nootropics (ampakines) work, what the science really shows, and why the gap between biology and brain supplements matters.
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Roon Team
July 4, 2026·10 min read
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Science
Glycine and the NMDA Receptor: The Co-Agonist Behind Learning and Memory
Discover how the glycine NMDA receptor relationship works as a coincidence detector driving learning and long-term potentiation in the brain.
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Roon Team
July 4, 2026·10 min read
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Science
Senolytics and the Aging Brain: Can Clearing "Zombie Cells" Protect Cognition?
Senolytics may protect the aging brain by clearing zombie cells. See what mouse studies and human trials actually show before buying the supplements.
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Roon Team
July 4, 2026·12 min read
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Vitamin C and the Brain: The Antioxidant Your Neurons Hoard
Your brain hoards vitamin C at 10x blood levels—here's why. Discover how ascorbate supports neurotransmitters, fights oxidative stress, and affects
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Roon Team
July 4, 2026·10 min read
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Phenylethylamine (PEA): The Brain's "Love Molecule" and Why Its Effects Vanish So Fast
Phenylethylamine triggers dopamine and euphoria—but vanishes in minutes. Learn why PEA supplements rarely work and what the science actually says.
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Roon Team
July 3, 2026·10 min read
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Semax and Selank: The Russian Peptide Nootropics, Examined Honestly
Semax and selank promise sharper focus and less anxiety. But what does the evidence actually support? An honest look at the research, gaps, and risks.
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Roon Team
July 3, 2026·11 min read
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Thiamine (B1) and Brain Energy: How One Vitamin Powers Your Focus
Discover how thiamine (B1) converts glucose into brain fuel, why low B1 causes brain fog, and who's at risk for thiamine deficiency affecting cognition.
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Roon Team
July 3, 2026·11 min read
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Science
Octopamine: A Trace-Amine "Fat Burner" With Almost No Human Evidence
Octopamine appears on fat-burner labels, but human evidence is nearly nonexistent. Learn what the science actually says before you buy.
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Roon Team
July 3, 2026·8 min read
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Fasoracetam: The Racetam Being Studied for ADHD
Fasoracetam is the only racetam studied in a real ADHD clinical trial. Learn what the evidence shows, who it may help, and its legal status.
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Roon Team
July 3, 2026·11 min read
#adhd+1
Science
Pramiracetam: The Choline-Uptake Racetam
Pramiracetam boosts choline uptake harder than most racetams. Learn how it works, optimal dosing, and why skipping choline is a mistake.
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Roon Team
July 3, 2026·11 min read
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Science
Phosphatidylserine for ADHD: What the Research Actually Shows
Does phosphatidylserine help ADHD? See what clinical trials actually show about dosing, effects on inattention, and how it compares to proven treatments.
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Roon Team
July 3, 2026·9 min read
#adhd
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Grape Seed Extract and Cognition: What Proanthocyanidins Actually Do for Processing Speed and Attention
Discover how grape seed extract proanthocyanidins may boost processing speed and attention. What the research actually shows about this quiet cognitive
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Roon Team
July 3, 2026·9 min read
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Rosemary and 1,8-Cineole: Can the Smell of an Herb Sharpen Your Mind?
Can rosemary aroma sharpen your mind? Explore the science behind 1,8-cineole, the compound linked to faster, more accurate cognitive performance.
R
Roon Team
July 3, 2026·10 min read
#memory
Science
Centrophenoxine: Does the "Anti-Aging Nootropic" Hold Up?
Centrophenoxine is marketed as an anti-aging nootropic, but how strong is the evidence? We break down the real science behind the claimed benefits.
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Roon Team
July 3, 2026·8 min read
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Science
How Much Creatine for Your Brain? Why Your Head May Need More Than Your Muscles
The standard 5g creatine dose may not reach your brain. Learn what science says about the right creatine dose for brain function and cognition.
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Roon Team
July 3, 2026·10 min read
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Science
DL-Phenylalanine (DLPA) and Mood: A Careful Look at the Evidence
DLPA is marketed as a natural mood booster, but how strong is the science? A clear-eyed look at dl-phenylalanine benefits, mechanisms, and research gaps.
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Roon Team
July 3, 2026·10 min read
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Science
Maca (Lepidium meyenii): What the Mood and Energy Trials Really Found
Maca promises better mood and energy, but what do human trials actually show? We break down the real evidence, strongest findings, and weakest claims.
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Roon Team
July 3, 2026·10 min read
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Schisandra chinensis: The Berry Adaptogen for Mental Endurance
Schisandra chinensis offers real cognitive benefits for mental endurance under stress. Learn what the science actually supports before adding it to your
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Roon Team
July 3, 2026·9 min read
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Science
Serotonin, Explained: The Brain Chemical That Governs Mood, Patience, and the Gut
What does serotonin really do? Beyond 'happiness,' it governs patience, digestion, and sleep. Discover the science behind the brain's most misunderstood
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Roon Team
June 27, 2026·11 min read
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Can You Grow New Brain Cells? Adult Neurogenesis, Explained
Adult neurogenesis is real—but only in specific brain regions. Learn what the latest science says and how exercise, sleep, and stress affect new neuron
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Roon Team
June 27, 2026·10 min read
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Science
The Endocannabinoid System: Your Brain's Built-In Balance Network (and the Real "Runner's High")
The endocannabinoid system controls mood, stress, and the real runner's high. Learn how your brain's built-in balance network actually works.
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Roon Team
June 27, 2026·10 min read
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Science
The Omega-3 Index: How to Measure Your Brain's Fatty-Acid Status
The omega-3 index brain test measures DHA and EPA in your cells. Learn why 8% is the target, what low levels mean, and how it affects cognition.
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Roon Team
June 27, 2026·11 min read
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Science
Methylxanthines Explained: The Caffeine, Theobromine, and Theophylline Family
Discover how methylxanthines—caffeine, theobromine, and theophylline—differ in structure and effects on your brain, lungs, and heart.
R
Roon Team
June 27, 2026·9 min read
#caffeine+2