Free U.S. shipping on orders $45+ · Subscribe & save

The Journal

All articles

Journal archive.

Page 7 of 61

SAMe (S-Adenosylmethionine): The Methyl Donor Behind Mood, Methylation, and a Calmer Brain
Science

SAMe (S-Adenosylmethionine): The Methyl Donor Behind Mood, Methylation, and a Calmer Brain

Discover how the SAMe supplement supports mood, neurotransmitter production, and methylation. Explore clinical evidence, dosage tips, and depression

R
Roon Team
June 25, 2026·11 min read
+3
CBD for Focus and Anxiety: What the Science Actually Supports (and Where It Sedates)
Science

CBD for Focus and Anxiety: What the Science Actually Supports (and Where It Sedates)

Does CBD really help anxiety and focus? See what clinical research actually shows, why dose matters, and where CBD sedates instead of sharpens.

R
Roon Team
June 25, 2026·10 min read
#anxiety
Kratom (Mitragynine): A Stimulant at Low Doses, an Opioid at High Doses, and the Honest Risk Picture
Science

Kratom (Mitragynine): A Stimulant at Low Doses, an Opioid at High Doses, and the Honest Risk Picture

Kratom acts as a stimulant at low doses and an opioid at high doses. Learn the real pharmacology, dose curve, and risk picture—no hype, just science.

R
Roon Team
June 25, 2026·11 min read
+2
Low-Dose Lithium Orotate for Brain Health: What the Science Actually Shows
Science

Low-Dose Lithium Orotate for Brain Health: What the Science Actually Shows

A 2025 Nature study changed what we know about low dose lithium orotate and brain health. Here's what the science actually shows—and what it doesn't.

R
Roon Team
June 25, 2026·12 min read
+3
Iodine and the Brain: The Thyroid-Cognition Connection
Science

Iodine and the Brain: The Thyroid-Cognition Connection

Discover how iodine and cognition are linked through thyroid hormones. Learn what the science says about iodine deficiency and your mental performance.

R
Roon Team
June 25, 2026·9 min read
+2
Zinc and Focus: The Overlooked Cognitive Mineral
Science

Zinc and Focus: The Overlooked Cognitive Mineral

Zinc for focus is underrated. Learn how this mineral shapes attention, memory, and brain function—and when supplementing actually makes a difference.

R
Roon Team
June 25, 2026·10 min read
#focus+2
Vitamin D Brain Fog: Why Low Levels Quietly Drain Your Focus
Science

Vitamin D Brain Fog: Why Low Levels Quietly Drain Your Focus

Low vitamin D could be behind your brain fog. Learn how vitamin D deficiency quietly drains focus and what you can do to fix it.

R
Roon Team
June 25, 2026·10 min read
+3
Vitamin B6 for the Brain: How It Builds Your Neurotransmitters (and Where the Toxicity Line Sits)
Science

Vitamin B6 for the Brain: How It Builds Your Neurotransmitters (and Where the Toxicity Line Sits)

Vitamin B6 drives dopamine, serotonin, and GABA production—but too much causes nerve damage. Learn the brain benefits and where the toxicity line sits.

R
Roon Team
June 25, 2026·10 min read
+3
Folate, Methylfolate, and the Brain: How MTHFR Shapes Mood and Cognition
Science

Folate, Methylfolate, and the Brain: How MTHFR Shapes Mood and Cognition

Discover how methylfolate supports brain function, why MTHFR gene variants matter, and how the right folate form affects mood, cognition, and

R
Roon Team
June 25, 2026·11 min read
+3
Cocoa Flavanols and the Brain: Blood Flow, Memory, and the Dose That Matters
Science

Cocoa Flavanols and the Brain: Blood Flow, Memory, and the Dose That Matters

Cocoa flavanols boost brain blood flow and memory—but dose matters. Learn what the research says and how much you actually need to see results.

R
Roon Team
June 24, 2026·10 min read
+2
Higenamine: The Beta-2 Agonist Hiding in "Fat Burners" (and Why It's Banned in Sport)
Science

Higenamine: The Beta-2 Agonist Hiding in "Fat Burners" (and Why It's Banned in Sport)

Higenamine is a WADA-banned beta-2 agonist hiding in fat burners and pre-workouts. Learn why it's prohibited in sport and how to spot it on labels.

R
Roon Team
June 24, 2026·9 min read
+3
P-Synephrine (Bitter Orange): The Ephedra Replacement, Examined Honestly
Science

P-Synephrine (Bitter Orange): The Ephedra Replacement, Examined Honestly

P-synephrine replaced ephedra in fat burners, but does it work? We examine the science on bitter orange extract's effectiveness and safety honestly.

R
Roon Team
June 24, 2026·10 min read
+3
Organic vs Synthetic Caffeine (PurCaf, Green Coffee): Does "Natural" Caffeine Work Differently?
Science

Organic vs Synthetic Caffeine (PurCaf, Green Coffee): Does "Natural" Caffeine Work Differently?

Natural caffeine vs synthetic caffeine—same molecule, but does it feel different? We break down the chemistry behind PurCaf, green coffee, and lab-made

R
Roon Team
June 24, 2026·10 min read
#caffeine+1
Caffeine-Pterostilbene Cocrystal (Purenergy): The Science of "More Caffeine, Longer"
Science

Caffeine-Pterostilbene Cocrystal (Purenergy): The Science of "More Caffeine, Longer"

Discover how the caffeine pterostilbene cocrystal Purenergy works, what human studies actually show, and whether slower absorption means better energy.

R
Roon Team
June 24, 2026·11 min read
#caffeine+2
Caffeine Citrate: The Fast-Onset Form Hospitals Use (and What It Teaches Us)
Science

Caffeine Citrate: The Fast-Onset Form Hospitals Use (and What It Teaches Us)

Caffeine citrate is used in NICUs for a reason. Learn how this fast-dissolving caffeine salt works, its true dosing math, and what pre-workout labels

R
Roon Team
June 24, 2026·10 min read
#caffeine+3
Dicaffeine Malate (Infinergy): Does "Buffered, Smooth-Release" Caffeine Hold Up?
Science

Dicaffeine Malate (Infinergy): Does "Buffered, Smooth-Release" Caffeine Hold Up?

Is dicaffeine malate really smoother and crash-free? We break down the chemistry behind Infinergy and why 'buffered caffeine' is mostly marketing.

R
Roon Team
June 24, 2026·9 min read
+2
Sulbutiamine: The Synthetic Vitamin B1 Built for Fatigue
Science

Sulbutiamine: The Synthetic Vitamin B1 Built for Fatigue

Sulbutiamine is a synthetic B1 vitamin built to cross the blood-brain barrier. Learn how it works, its proven benefits for fatigue, and the right dosage.

R
Roon Team
June 24, 2026·10 min read
+3
Oxiracetam: The "Stimulatory" Racetam, Examined
Science

Oxiracetam: The "Stimulatory" Racetam, Examined

Is oxiracetam really a stimulatory racetam? We break down the science, clinical research, legal status, and what the evidence actually supports.

R
Roon Team
June 24, 2026·10 min read
+2
Aniracetam: The Fat-Soluble AMPA Modulator for Mood and Focus
Science

Aniracetam: The Fat-Soluble AMPA Modulator for Mood and Focus

Discover how aniracetam works as a fat-soluble AMPA modulator, why its bioavailability is just 0.2%, and what the research says about mood and cognition.

R
Roon Team
June 24, 2026·12 min read
+3
Broccoli Sprouts vs Sulforaphane Supplements: Getting the Real Compound
Science

Broccoli Sprouts vs Sulforaphane Supplements: Getting the Real Compound

Most sulforaphane supplements don't contain real sulforaphane. Learn why broccoli sprouts vs sulforaphane supplements matters and how to actually get the

R
Roon Team
June 24, 2026·8 min read
+2
Sulforaphane: How Broccoli's Nrf2 Activator Protects the Brain
Science

Sulforaphane: How Broccoli's Nrf2 Activator Protects the Brain

Discover how sulforaphane activates Nrf2 to shield your brain from oxidative stress. Learn what the science says and where the hype exceeds the evidence.

R
Roon Team
June 24, 2026·11 min read
+2
Spermidine: The Autophagy-Activating Longevity Compound
Science

Spermidine: The Autophagy-Activating Longevity Compound

Spermidine triggers autophagy—your cells' self-cleaning process. Learn how it supports longevity, memory, and heart health through diet and

R
Roon Team
June 24, 2026·11 min read
+2
Nicotinamide Riboside for Brain Health: What Human Trials Actually Show
Science

Nicotinamide Riboside for Brain Health: What Human Trials Actually Show

NR raises NAD+ in the brain, but do human trials show cognitive benefits? See what the actual research reveals about nicotinamide riboside and brain

R
Roon Team
June 24, 2026·10 min read
+3
Low-Dose Methylene Blue and the Brain: A Cautious, Evidence-Based Look
Science

Low-Dose Methylene Blue and the Brain: A Cautious, Evidence-Based Look

Methylene blue brain benefits are real but conditional. Explore the human data, U-shaped dosing risks, and who should avoid it entirely.

R
Roon Team
June 24, 2026·11 min read
+2